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Therapy Name | KP372-1 |
Synonyms | |
Therapy Description |
KP372-1 is an inhibitor of AKT that results in inhibition of downstream signaling, thereby leading to apoptotic activity and blockade of cell proliferation (PMID: 15870708). |
Drug Name | Trade Name | Synonyms | Drug Classes | Drug Description |
---|---|---|---|---|
KP372-1 | Akt Inhibitor (Pan) 20 | KP372-1 is an inhibitor of AKT that results in inhibition of downstream signaling, thereby leading to apoptotic activity and blockade of cell proliferation (PMID: 15870708). |
Molecular Profile | Indication/Tumor Type | Response Type | Therapy Name | Approval Status | Evidence Type | Efficacy Evidence | References |
---|---|---|---|---|---|---|---|
Unknown unknown | triple-receptor negative breast cancer | not applicable | KP372-1 | Preclinical - Cell culture | Actionable | In a preclinical study, KP372-1 induced complete growth inhibition of triple-receptor negative breast cancer cells in culture (PMID: 27872098). | 27872098 |
Clinical Trial | Phase | Therapies | Title | Recruitment Status | Covered Countries | Other Countries |
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