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|Drug Name||Trade Name||Synonyms||Drug Classes||Drug Description|
|SIM-89||MET Inhibitor 51 TrkA Receptor Inhibitor 8||SIM-89 is an inhibitor of c-MET, TRKA, and AMPK, which may result in antitumor activity including inhibition of cell proliferation and suppression of cell migration (PMID: 28332364).|
|Molecular Profile||Indication/Tumor Type||Response Type||Therapy Name||Approval Status||Evidence Type||Efficacy Evidence||References|
|Unknown unknown||lung non-small cell carcinoma||not applicable||SIM-89||Preclinical - Cell culture||Actionable||In a preclinical study, non-small cell lung carcinoma cells demonstrated inhibition of cell proliferation and suppressed cell migration when treated with SIM-89 in culture (PMID: 28332364).||28332364|
|Clinical Trial||Phase||Therapies||Title||Recruitment Status|