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|Drug Name||Trade Name||Synonyms||Drug Classes||Drug Description|
|GNE-781||GNE-781 is an inhibitor that targets the bromodomain of CREBBP and EP300, which results in suppression of Myc, and subsequently, may lead to antitumor activity (PMID: 28892380).|
|Molecular Profile||Indication/Tumor Type||Response Type||Therapy Name||Approval Status||Evidence Type||Efficacy Evidence||References|
|Unknown unknown||acute myeloid leukemia||not applicable||GNE-781||Preclinical - Cell line xenograft||Actionable||In a preclinical study, GNE-781 treatment resulted in tumor growth inhibition and reduced MYC transcript levels in acute myeloid leukemia cell line xenograft models (PMID: 28892380).||28892380|
|Clinical Trial||Phase||Therapies||Title||Recruitment Status|