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|Drug Name||Trade Name||Synonyms||Drug Classes||Drug Description|
|INCB7839||Aderbasib|INCB007839||INCB7839 (Aderbasib) is an inhibitor of ADAM10 and ADAM17, which may indirectly block shedding of ERBB2 (HER2), thereby potentially leading to antitumor activity (PMID: 18757423, PMID: 29230082).|
|Molecular Profile||Indication/Tumor Type||Response Type||Therapy Name||Approval Status||Evidence Type||Efficacy Evidence||References|
|Clinical Trial||Phase||Therapies||Title||Recruitment Status|
|NCT04295759||Phase I||INCB7839||INCB7839 in Treating Children With Recurrent/Progressive High-Grade Gliomas||Recruiting|