Therapy Detail

Therapy Name ABBV-321
Therapy Description

ABBV-321 is an antibody-drug conjugate consisting of a monoclonal EGFR antibody and the cytotoxic agent, pyrrolobenzodiazepine (NCI Drug Dictionary).

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Drug Name Trade Name Synonyms Drug Classes Drug Description
ABBV-321 EGFR Antibody 27 ABBV-321 is an antibody-drug conjugate consisting of a monoclonal EGFR antibody and the cytotoxic agent, pyrrolobenzodiazepine (NCI Drug Dictionary).
Molecular Profile Indication/Tumor Type Response Type Therapy Name Approval Status Evidence Type Efficacy Evidence References
Clinical Trial Phase Therapies Title Recruitment Status
NCT03234712 Phase I ABBV-321 A Study Evaluating the Safety, Pharmacokinetics, and Anti-tumor Activity of ABBV-321 in Subjects With Advanced Solid Tumors Associated With Overexpression of the Epidermal Growth Factor Receptor (EGFR) or Its Ligands Recruiting