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|Drug Name||Trade Name||Synonyms||Drug Classes||Drug Description|
|AXL CAR-T cells||AXL CAR-T cells are T-cells that are modified to express a chimeric antigen receptor recognizing AXL, which may result in increased death of AXL-expressing tumor cells upon infusion (PMID: 29497107).|
|Molecular Profile||Indication/Tumor Type||Response Type||Therapy Name||Approval Status||Evidence Type||Efficacy Evidence||References|
|AXL positive||chronic myeloid leukemia||sensitive||AXL CAR-T cells||Preclinical - Cell culture||Actionable||In a preclinical study, treatment with AXL CAR-T cells led to induced death of AXL-expressing chronic myeloid leukemia (CML) cells and did not induce death of AXL-negative CML cells in culture (PMID: 29497107).||29497107|
|Clinical Trial||Phase||Therapies||Title||Recruitment Status||Covered Countries||Other Countries|