Therapy Detail
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| Therapy Name | MTX110 |
| Synonyms | |
| Therapy Description |
MTX110 is a nanoparticle formulation of Panobinostat which can be delivered into the brain via convection-enhanced delivery (PMID: 29856296, PMID: 32357333). |
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| Drug Name | Trade Name | Synonyms | Drug Classes | Drug Description |
|---|---|---|---|---|
| MTX110 | MTX-110|MTX 110 | MTX110 is a nanoparticle formulation of Panobinostat which can be delivered into the brain via convection-enhanced delivery (PMID: 29856296, PMID: 32357333). |
Filtering
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- Use simple literal full or partial string matches
- Separate multiple filter terms with a space. Any order may be used (i. e. a b c and c b a are equivalent )
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- Use quotes to match on a longer phrase with spaces (i.e. "mtor c1483f")
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| Molecular Profile | Indication/Tumor Type | Response Type | Therapy Name | Approval Status | Evidence Type | Efficacy Evidence | References |
|---|
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- Use quotes to match on a longer phrase with spaces (i.e. "mtor c1483f")
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| Clinical Trial | Phase | Therapies | Title | Recruitment Status | Covered Countries | Other Countries |
|---|---|---|---|---|---|---|
| NCT04315064 | Phase I | MTX110 | Infusion of Panobinostat (MTX110) Into the Fourth Ventricle in Children and Adults With Recurrent Medulloblastoma | Recruiting | USA | 0 |
| NCT05324501 | Phase I | MTX110 Lomustine + MTX110 | A Study of Intra-tumoral Administered MTX110 in Patients With Recurrent Glioblastoma (MAGIC-G1) | Active, not recruiting | USA | 0 |
| NCT03566199 | Phase Ib/II | MTX110 | MTX110 by Convection-Enhanced Delivery in Treating Participants With Newly-Diagnosed Diffuse Intrinsic Pontine Glioma (PNOC015) | Completed | USA | 0 |
| NCT04264143 | Phase I | MTX110 | CED of MTX110 Newly Diagnosed Diffuse Midline Gliomas | Completed | USA | 0 |
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