Therapy Detail
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| Therapy Name | PCA062 |
| Synonyms | |
| Therapy Description |
PCA062 is an antibody drug conjugate comprised of maytansinoid DM1 and a monoclonal antibody specific to CDH3, which may lead to cytotoxicity of CHD3-expressing tumor cells (Cancer Res 2015;75(15 Suppl):Abstract nr 1682). |
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| Drug Name | Trade Name | Synonyms | Drug Classes | Drug Description |
|---|---|---|---|---|
| PCA062 | PCA062 is an antibody-drug conjugate (ADC) comprised of a monoclonal antibody specific to CDH3 linked to the anti-microtubule agent DM1, which may lead to cytotoxicity of CDH3-expressing tumor cells (Cancer Res 2015;75(15 Suppl):Abstract nr 1682). |
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- Simple literal full or partial string matches
- Separate multiple filter terms with a spaces, order doesn't matter (a b c and c b a are equivalent )
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- Use quotes to match a longer phrase which contains spaces "mtor c1483f"
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| Molecular Profile | Indication/Tumor Type | Response Type | Therapy Name | Approval Status | Evidence Type | Efficacy Evidence | References |
|---|
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- Simple literal full or partial string matches
- Separate multiple filter terms with a spaces, order doesn't matter (a b c and c b a are equivalent )
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- Use quotes to match a longer phrase which contains spaces "mtor c1483f"
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- Generally, the default sort order for tables is set to be first column ascending, however, specific tables may set a different default sort order.
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| Clinical Trial | Phase | Therapies | Title | Recruitment Status | Covered Countries | Other Countries |
|---|---|---|---|---|---|---|
| NCT02375958 | Phase I | PCA062 | PCA062 in pCAD-positive Tumors. | Completed | USA | 5 |
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