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Therapy Name BAY 2315497
Synonyms
Therapy Description

BAY 2315497 (PSMA-TTC) comprises an antibody targeting PSMA radiolabeled with thorium-227, which may decrease growth of PSMA-expressing tumors (Cancer Res July 1 2017 (77) (13 Supplement) 5200, PMID: 31831560).

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Drug Name Trade Name Synonyms Drug Classes Drug Description
BAY 2315497 PSMA-TTC|BAY2315497|BAY-2315497 PSMA Antibody 20 BAY 2315497 (PSMA-TTC) comprises an antibody targeting PSMA radiolabeled with thorium-227, which may decrease growth of PSMA-expressing tumors (Cancer Res July 1 2017 (77) (13 Supplement) 5200, PMID: 31831560).

Filtering

  • Case insensitive filtering will display rows if any text in any cell matches the filter term
  • Use simple literal full or partial string matches
  • Separate multiple filter terms with a space. Any order may be used (i. e. a b c and c b a are equivalent )
  • Filtering will only apply to rows that are already loaded on the page. Filtering has no impact on query parameters.
  • Use quotes to match on a longer phrase with spaces (i.e. "mtor c1483f")

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  • Generally, the default sort order for tables is set to be first column ascending; however, specific tables may set a different default sort order.
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Molecular Profile Indication/Tumor Type Response Type Therapy Name Approval Status Evidence Type Efficacy Evidence References

Filtering

  • Case insensitive filtering will display rows if any text in any cell matches the filter term
  • Use simple literal full or partial string matches
  • Separate multiple filter terms with a space. Any order may be used (i. e. a b c and c b a are equivalent )
  • Filtering will only apply to rows that are already loaded on the page. Filtering has no impact on query parameters.
  • Use quotes to match on a longer phrase with spaces (i.e. "mtor c1483f")

Sorting

  • Generally, the default sort order for tables is set to be first column ascending; however, specific tables may set a different default sort order.
  • Click on any column header arrows to sort by that column
  • Hold down the Shift key and click multiple columns to sort by more than one column. Be sure to set ascending or descending order for a given column before moving on to the next column.

Clinical Trial Phase Therapies Title Recruitment Status Covered Countries Other Countries
NCT03724747 Phase I BAY 2315497 Study to Evaluate the Safety, Tolerability,Pharmacokinetics, and Anti-tumor Activity of a Thorium-227 Labeled Antibody-chelator Conjugate, in Patients With Metastatic Castration Resistant Prostate Cancer Active, not recruiting USA | GBR 1


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