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|Drug Name||Trade Name||Synonyms||Drug Classes||Drug Description|
|VS-II-173||PIM1 Inhibitor 2 PIM3 Inhibitor 1||VS-II-173 is a kinase inhibitor of PIM1 and PIM3, which may induce apoptosis, specifically in cells with Pim activity, such as acute myeloid leukemia cells (PMID: 30679386).|
|Molecular Profile||Indication/Tumor Type||Response Type||Therapy Name||Approval Status||Evidence Type||Efficacy Evidence||References|
|Unknown unknown||acute myeloid leukemia||not applicable||VS-II-173||Preclinical - Cell culture||Actionable||In a preclinical study, treatment with VS-II-173 induced apoptotic activity in acute myeloid leukemia cells in culture and resulted in reduced Pim kinase-mediated signaling (PMID: 30679386).||30679386|
|Clinical Trial||Phase||Therapies||Title||Recruitment Status|