Therapy Detail

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Therapy Name 177Lu-edotreotide
Synonyms
Therapy Description

177Lu-edotreotide is a radioconjugate comprising the somatostatin analog edotreotide linked to Lu 177, which may have anti-tumor activity (NCI Drug Dictionary).

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Drug Name Trade Name Synonyms Drug Classes Drug Description
177Lu-edotreotide 177LuDOTATOC|177Lu-DOTA-Tyr3-octreotide|177Lu-Edo 177Lu-edotreotide is a radioconjugate comprising the somatostatin analog edotreotide linked to Lu 177, which may have anti-tumor activity (NCI Drug Dictionary).

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Molecular Profile Indication/Tumor Type Response Type Therapy Name Approval Status Evidence Type Efficacy Evidence References

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Clinical Trial Phase Therapies Title Recruitment Status Covered Countries Other Countries
NCT03049189 Phase III 177Lu-edotreotide Everolimus Efficacy and Safety of 177Lu-edotreotide PRRT in GEP-NET Patients (COMPETE) Active, not recruiting USA | NLD | ITA | GBR | FRA | ESP | DEU | BEL | AUT | AUS 4
NCT04919226 Phase III Fluorouracil + Leucovorin + Oxaliplatin 177Lu-edotreotide Everolimus Capecitabine + Temozolomide Lutetium 177Lu-Edotreotide Versus Best Standard of Care in Well-differentiated Aggressive Grade-2 and Grade-3 GastroEnteroPancreatic NeuroEndocrine Tumors (GEP-NETs) - COMPOSE (COMPOSE) Recruiting USA | NLD | ITA | GBR | FRA | ESP | DEU | AUS 2
NCT05918302 Phase III 177Lu-edotreotide Everolimus Efficacy and Safety of Radiotherapy Compared to Everolimus in Somatostatin Receptor Positive Neuroendocrine Tumors of the Lung and Thymus. (LEVEL) Recruiting ITA | FRA | ESP 0


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