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Therapy Name BAY2701439
Synonyms
Therapy Description

BAY2701439 comprises a monoclonal antibody that targets ERBB2 (HER2) conjugated to a chelator complexed with the radioisotope Th 227, which delivers radiation to ERBB2 (HER2-expressing tumors and has potential antitumor activity (Cancer Res 2021;81(13_Suppl):Abstract nr ND07).

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Drug Name Trade Name Synonyms Drug Classes Drug Description
BAY2701439 BAY-2701439|BAY 2701439|HER2-TTC|227Th Trastuzumab Corixetan HER2 (ERBB2) Antibody 72 BAY2701439 comprises a monoclonal antibody that targets ERBB2 (HER2) conjugated to a chelator complexed with the radioisotope Th 227, which delivers radiation to ERBB2 (HER2-expressing tumors and has potential antitumor activity (Cancer Res 2021;81(13_Suppl):Abstract nr ND07).

Filtering

  • Case insensitive filtering will display rows if any text in any cell matches the filter term
  • Use simple literal full or partial string matches
  • Separate multiple filter terms with a space. Any order may be used (i. e. a b c and c b a are equivalent )
  • Filtering will only apply to rows that are already loaded on the page. Filtering has no impact on query parameters.
  • Use quotes to match on a longer phrase with spaces (i.e. "mtor c1483f")

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Molecular Profile Indication/Tumor Type Response Type Therapy Name Approval Status Evidence Type Efficacy Evidence References

Filtering

  • Case insensitive filtering will display rows if any text in any cell matches the filter term
  • Use simple literal full or partial string matches
  • Separate multiple filter terms with a space. Any order may be used (i. e. a b c and c b a are equivalent )
  • Filtering will only apply to rows that are already loaded on the page. Filtering has no impact on query parameters.
  • Use quotes to match on a longer phrase with spaces (i.e. "mtor c1483f")

Sorting

  • Generally, the default sort order for tables is set to be first column ascending; however, specific tables may set a different default sort order.
  • Click on any column header arrows to sort by that column
  • Hold down the Shift key and click multiple columns to sort by more than one column. Be sure to set ascending or descending order for a given column before moving on to the next column.

Clinical Trial Phase Therapies Title Recruitment Status Covered Countries Other Countries
NCT04147819 Phase I BAY2701439 A First in Human Study of BAY2701439 to Look at Safety, How the Body Absorbs, Distributes and Excretes the Drug, and How Well the Drug Works in Participants With Advanced Cancer Expressing the HER2 Protein Completed USA | GBR 0


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