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|Therapy Name||Anti-FLT3 CAR-T cells|
|Drug Name||Trade Name||Synonyms||Drug Classes||Drug Description|
|Anti-FLT3 CAR-T cells||AMG553|AMG-553||Anti-FLT3 CAR-T cells are autologous T-cells engineered to express a chimeric antigen receptor targeting FLT3, which potentially induces cytotoxic immune response against FLT3-expressing tumor cells (Journal of Clinical Oncology 2019 37:15_suppl, 7032).|
|Molecular Profile||Indication/Tumor Type||Response Type||Therapy Name||Approval Status||Evidence Type||Efficacy Evidence||References|
|Clinical Trial||Phase||Therapies||Title||Recruitment Status|
|NCT03904069||Phase I||Anti-FLT3 CAR-T cells||Study Evaluating the Safety, Tolerability, and Efficacy of FLT3 CAR-T AMG 553 in FLT3-positive Relapsed/Refractory AML||Not yet recruiting|