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| NCT ID | NCT03037385 |
| Title | Phase 1/2 Study of the Highly-selective RET Inhibitor, Pralsetinib (BLU-667), in Participants With Thyroid Cancer, Non-Small Cell Lung Cancer, and Other Advanced Solid Tumors (ARROW) |
| Acronym | ARROW |
| Recruitment | Completed |
| Gender | both |
| Phase | Phase Ib/II |
| Variant Requirements | Yes |
| Sponsors | Blueprint Medicines Corporation |
| Indications | |
| Therapies | |
| Age Groups: | adult | senior |
| Covered Countries | USA | NLD | ITA | GBR | FRA | ESP | DEU | BEL |
| Facility | Status | City | State | Zip | Country | Details |
|---|---|---|---|---|---|---|
| Mayo Clinic Hospital | Phoenix | Arizona | 85054 | United States | Details | |
| UC Irvine Medical Center | Orange | California | 92868 | United States | Details | |
| University of Colorado Anschutz Medical Campus | Aurora | Colorado | 80045 | United States | Details | |
| Georgetown University Medical Center | Washington | District of Columbia | 20007 | United States | Details | |
| Mayo Clinic-Jacksonville | Jacksonville | Florida | 32224 | United States | Details | |
| Sylvester Comprehensive Cancer Center; University of Miami School of Medicine | Miami | Florida | 33136 | United States | Details | |
| Maryland Oncology Hematology, P.A. | Columbia | Maryland | 21044 | United States | Details | |
| Massachusetts General Hospital. | Boston | Massachusetts | 02114 | United States | Details | |
| University of Michigan | Ann Arbor | Michigan | 48109-0934 | United States | Details | |
| Mayo Clinic Rochester | Rochester | Minnesota | 55902 | United States | Details | |
| Washington University School of Medicine in St. Louis | Saint Louis | Missouri | 63110 | United States | Details | |
| Albany Medical Center | Albany | New York | 12208 | United States | Details | |
| Weill Cornell Medical College-New York Presbyterian Hospital | New York | New York | 10021 | United States | Details | |
| Oregon Health & Science University | Portland | Oregon | 97239 | United States | Details | |
| Stellar - Chance Laboratories | Philadelphia | Pennsylvania | 19104 | United States | Details | |
| Texas Oncology-Austin Midtown | Austin | Texas | 78705 | United States | Details | |
| Texas Oncology - Baylor Charles A. Sammons Cancer Center | Dallas | Texas | 75246 | United States | Details | |
| The University of Texas MD Anderson Cancer Center | Houston | Texas | 77030-4009 | United States | Details | |
| Seattle Cancer Care Alliance | Seattle | Washington | 98109 | United States | Details | |
| Antwerp University Hospital | Edegem | 2650 | Belgium | Details | ||
| Beijing Cancer Hospital | Beijing | 100142 | China | Details | ||
| The affiliated Cancer Hospital, School of Medicine, UESTC | Chengdu | 610041 | China | Details | ||
| West China Hospital, Sichuan University | Chengdu | 610041 | China | Details | ||
| Chongqing Cancer Hospital | Chongqing | 400030 | China | Details | ||
| Fujian Provincial Cancer Hospital | Fuzhou City | 350014 | China | Details | ||
| First Affiliated Hospital of Gannan Medical University | Ganzhou | 341000 | China | Details | ||
| Sun Yet-sen University Cancer Center | Guangzhou City | 510663 | China | Details | ||
| Guangdong General Hospital | Guangzhou | 510080 | China | Details | ||
| Zhejiang Provincial People?s Hospital | Hangzhou | 310014 | China | Details | ||
| Jinan Central Hospital | Jinan City | 250013 | China | Details | ||
| Gansu Cancer Hospital | Lanzhou | 730050 | China | Details | ||
| Fudan University Shanghai Cancer Center | Shanghai City | 200120 | China | Details | ||
| Tianjin Medical University Cancer Institute & Hospital | Tianjin | 3000060 | China | Details | ||
| Union Hospital Tongji Medical College Huazhong University of Science and Technology | Wuhan City | 430023 | China | Details | ||
| Zhejiang Cancer Hospital | Zhejiang | 310022 | China | Details | ||
| Henan Cancer Hospital | Zhengzhou | 450008 | China | Details | ||
| Institut Bergonie | Bordeaux | 33076 | France | Details | ||
| Centre Hospitalier Régional Universitaire de Lille (CHRU) - Hôpital Claude Huriez | Lille | 59037 | France | Details | ||
| Centre Léon Bérard | Lyon | 69373 | France | Details | ||
| Centre Antoine Lacassagne | Nice | 06189 | France | Details | ||
| Institut Curie | Paris | 75005 | France | Details | ||
| CHU de Rennes - Hopital de Pontchaillo | Rennes | 35033 | France | Details | ||
| Hôpital Larrey;Université Paul Sabatier | Toulouse | 31059 | France | Details | ||
| Gustave Roussy | Villejuif | 94805 | France | Details | ||
| Helios Klinikum Emil von Behring GmbH | Berlin | 14165 | Germany | Details | ||
| Universitätsklinikum Essen; Innere Klinik und Poliklinik für Tumorforschung | Essen | 45122 | Germany | Details | ||
| Thoraxklinik Heidelberg gGmbH | Heidelberg | 69126 | Germany | Details | ||
| Klinikum der Universität München | Muenchen | 80336 | Germany | Details | ||
| Pius-Hospital; Klinik fuer Haematologie und Onkologie | Oldenburg | 26121 | Germany | Details | ||
| The Chinese University of Hong Kong | Shatin | 123456 | Hong Kong | Details | ||
| Ospedale Santa Maria Delle Croci | Ravenna | Emilia-Romagna | 48100 | Italy | Details | |
| Istituto Nazionale Tumori Regina Elena | Roma | Lazio | 00144 | Italy | Details | |
| IEO; Divisione di Sviluppo di Nuovi Farmaci per Terapie Innovative | Milano | Lombardia | 20141 | Italy | Details | |
| Asst Grande Ospedale Metropolitano Niguarda | Milano | Lombardia | 20162 | Italy | Details | |
| Seoul National University Hospital | Seoul | 03080 | Korea, Republic of | Details | ||
| Asan Medical Center | Seoul | 05505 | Korea, Republic of | Details | ||
| Samsung Medical Center | Seoul | 06351 | Korea, Republic of | Details | ||
| Severance Hospital, Yonsei University Health System; Oncology | Seoul | 120-752 | Korea, Republic of | Details | ||
| Antoni van Leeuwenhoek Ziekenhuis | Amsterdam | 1066 CX | Netherlands | Details | ||
| Universitair Medisch Centrum Groningen | Groningen | 9713 GZ | Netherlands | Details | ||
| National Cancer Centre | Singapore | 169610 | Singapore | Details | ||
| Institut Catala d Oncologia Hospitalet | Hospitalet de Llobregat | Barcelona | 08908 | Spain | Details | |
| Vall d?Hebron Institute of Oncology (VHIO), Barcelona | Barcelona | 08035 | Spain | Details | ||
| Hospital Clinic de Barcelona | Barcelona | 08036 | Spain | Details | ||
| Hospital Ramon y Cajal; Servicio de Oncologia | Madrid | 28034 | Spain | Details | ||
| Hospital Universitario 12 de Octubre; Servicio de Oncologia | Madrid | 28041 | Spain | Details | ||
| Taipei Veterans General Hospital | Taipei City | 11217 | Taiwan | Details | ||
| National Taiwan University Hospital | Taipei | 10002 | Taiwan | Details | ||
| Guys and St Thomas NHS Foundation Trust, Guys Hospital | London | SE1 9RT | United Kingdom | Details | ||
| Sarah Cannon Research Institute | London | W1G 6AD | United Kingdom | Details | ||
| University College London Hospitals NHS Foundation Trust; NIHR UCLH Clinical Research Facility | London | W1T 7HA | United Kingdom | Details | ||
| The Christie NHS Foundation Trust | Manchester | M20 4BX | United Kingdom | Details |