Clinical Trial Detail


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NCT ID NCT03037385
Title Phase 1/2 Study of the Highly-selective RET Inhibitor, Pralsetinib (BLU-667), in Patients With Thyroid Cancer, Non-Small Cell Lung Cancer, and Other Advanced Solid Tumors (ARROW)
Recruitment Recruiting
Gender both
Phase Phase Ib/II
Variant Requirements Yes
Sponsors Blueprint Medicines Corporation

Advanced Solid Tumor

thyroid gland medullary carcinoma

lung non-small cell carcinoma



Age Groups: adult | senior
Covered Countries USA

Facility Status City State Zip Country Details
Mayo Clinic Recruiting Phoenix Arizona 85054 United States Details
UC Irvine Medical Center Recruiting Orange California 92868 United States Details
University of Colorado Cancer Center Recruiting Aurora Colorado 80045 United States Details
Georgetown University Medical Center Recruiting Washington District of Columbia 20007 United States Details
Mayo Clinic Recruiting Jacksonville Florida 32224 United States Details
University of Miami Hospitals and Clinics, Sylvester Comprehensive Cancer Center Recruiting Miami Florida 33136 United States Details
Maryland Oncology Hematology, PA - Columbia Recruiting Columbia Maryland 21044-3257 United States Details
Massachusetts General Hospital Recruiting Boston Massachusetts 02114 United States Details
University of Michigan Recruiting Ann Arbor Michigan 48109 United States Details
Mayo Clinic Recruiting Rochester Minnesota 55905 United States Details
Washington University School of Medicine, Siteman Cancer Center Recruiting Saint Louis Missouri 63110 United States Details
Albany Medical Center Recruiting Albany New York 12208-3412 United States Details
Jack D. Weiler Hospital Recruiting Bronx New York 10461-2301 United States Details
Cornell University Recruiting New York New York 10021 United States Details
Oregon Health and Science University Recruiting Portland Oregon 97239 United States Details
University of Pennsylvania Hospital Recruiting Philadelphia Pennsylvania 19104 United States Details
UPMC CancerCenter Recruiting Pittsburgh Pennsylvania 15213-1862 United States Details
Texas Oncology - Austin Recruiting Austin Texas 78705-1165 United States Details
Texas Oncology - Baylor Charles A. Sammons Cancer Center Recruiting Dallas Texas 75246 United States Details
University of Texas MD Anderson Cancer Center Recruiting Houston Texas 77030 United States Details
University of Washington, Seattle Cancer Care Alliance Recruiting Seattle Washington 98109 United States Details
Antwerp University Hospital Recruiting Edegem 2650 Belgium Details
Beijing Cancer Hospital Recruiting Beijing 100036 China Details
West China Hospital, Sichuan University Recruiting Chengdu 610041 China Details
Sichuan Cancer Hospital & Institute Recruiting Chongqing 400030 China Details
Chongqing Cancer Hospital Recruiting Chongqing 404100 China Details
Fujian Provincial Cancer Hospital Recruiting Fuzhou 350014 China Details
First Affiliated Hospital of Gannan Medical University Recruiting Ganzhou 341000 China Details
Sun Yat-sen University Cancer Center Recruiting Guangzhou 510060 China Details
Guangdong Provincial People's Hospital Recruiting Guangzhou 510080 China Details
Nanfang Hospital of Southern Medical University Recruiting Guangzhou 510515 China Details
Zhejiang Provincial People's Hospital Recruiting Hangzhou 310000 China Details
Zhejiang Cancer Hospital Recruiting Hangzhou 310022 China Details
Anhui Provincial Cancer Hospital Recruiting Hefei 230031 China Details
Jinan Central Hospital Recruiting Jinan 250013 China Details
Gansu Provincial Cancer Hospital Recruiting Lanzhou 730050 China Details
Fudan University Shanghai Cancer Center Recruiting Shanghai 200032 China Details
Liaoning Cancer Hospital & Institute Recruiting Shenyang 110042 China Details
Tianjin Medical University Cancer Institute and Hospital Recruiting Tianjin 300041 China Details
Union Hospital, Tongji Medical College, Huazhong University of Science and Technology Recruiting Wuhan 430022 China Details
Henan Cancer Hospital Recruiting Zhengzhou 450008 China Details
Institut Bergonié Recruiting Bordeaux 33076 France Details
CHRU de Lille - Hôpital Claude Hurier Servide d'Endocrinologie et Diabétologie Recruiting Lille 59037 France Details
Centre Leon Berard Recruiting Lyon 69373 France Details
Centre Antoine Lacassagne Recruiting Nice 6100 France Details
Hospital Tenon Recruiting Paris 75020 France Details
Institut Curie Recruiting Paris 75248 France Details
CHU de Rennes - Hôpital Pontchaillou Recruiting Rennes 35033 France Details
Insitut Claudius Regaud Recruiting Toulouse 31059 France Details
Gustave Roussy Recruiting Villejuif 94805 France Details
HELIOS Klinikum Emil von Behring Recruiting Berlin 14165 Germany Details
Universitätsklinikum Essen Recruiting Essen 45147 Germany Details
Thoraxklinik Heidelberg Recruiting Heidelberg 69126 Germany Details
Klinikum der Universitat Munchen Recruiting Munich 81377 Germany Details
Pius-Hospital Oldenberg Recruiting Oldenburg 26121 Germany Details
The Chinese University of Hong Kong Recruiting Hong Kong Hong Kong Details
Istituto Europeo di Oncologia Sviluppo Nuovi Farmaci per Terapie Innovative Recruiting Milano 20141 Italy Details
Grande Ospedale Metropolitano Niguarda Recruiting Milan 20162 Italy Details
Ospedale Santa Maria delle Croci Recruiting Ravenna 48124 Italy Details
Istituto Nazionale Tumori Regina Elena Recruiting Rome 144 Italy Details
Seoul National University Hospital Recruiting Seoul 03080 Korea, Republic of Details
Severance Hospital Recruiting Seoul 03722 Korea, Republic of Details
Asan Medical Center Recruiting Seoul 05505 Korea, Republic of Details
Samsung Medical Center Recruiting Seoul 6351 Korea, Republic of Details
Nederlands Kanker Instituut - Antoni van Leeuwenhoek Ziekenhuis Recruiting Amsterdam 1066 CX Netherlands Details
University Medical Center Groningen Recruiting Groningen 9713 Netherlands Details
National Cancer Centre Singapore Recruiting Singapore 169160 Singapore Details
Hospital Universitari Vall d'Hebron Recruiting Barcelona 08035 Spain Details
Hospital Clinic Barcelona Recruiting Barcelona 08036 Spain Details
Hospital Duran I Reynals Recruiting Barcelona 08908 Spain Details
Hospital Universitario Ramon y Cajal Recruiting Madrid 28034 Spain Details
Hospital Universitario 12 de Octubre Servicio de Oncologia Medica Recruiting Madrid 28041 Spain Details
National Taiwan University Hospital Recruiting Taipei City 10002 Taiwan Details
Taipei Veterans General Hospital Recruiting Taipei 11217 Taiwan Details
NHS Grampian - Aberdeen Royal Infirmary Recruiting Aberdeen AB25 2ZN United Kingdom Details
Sarah Cannon Research Institute Recruiting London W1G 6AD United Kingdom Details
Guy's Hospital St. Thomas NHS Foundation Trust Recruiting London United Kingdom Details
NIHR UCLH Clinical Research Facility, University College of London NHS Foundation Trust Recruiting London United Kingdom Details
The Christie NHS Foundation Trust Recruiting Manchester United Kingdom Details
*Shaded cells indicate that there was no data available from for the field