Clinical Trial Detail


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NCT ID NCT03037385
Title Phase 1/2 Study of the Highly-selective RET Inhibitor, Pralsetinib (BLU-667), in Patients With Thyroid Cancer, Non-Small Cell Lung Cancer, and Other Advanced Solid Tumors (ARROW)
Recruitment Active, not recruiting
Gender both
Phase Phase Ib/II
Variant Requirements Yes
Sponsors Blueprint Medicines Corporation

Advanced Solid Tumor

thyroid gland medullary carcinoma

lung non-small cell carcinoma



Age Groups: adult | senior
Covered Countries USA | ITA | FRA | ESP | DEU

Facility Status City State Zip Country Details
Mayo Clinic Hospital Phoenix Arizona 85054 United States Details
UC Irvine Medical Center Orange California 92868 United States Details
University of Colorado Anschutz Medical Campus Aurora Colorado 80045 United States Details
Georgetown University Medical Center Washington District of Columbia 20007 United States Details
Mayo Clinic-Jacksonville Jacksonville Florida 32224 United States Details
Sylvester Comprehensive Cancer Center; University of Miami School of Medicine Miami Florida 33136 United States Details
Maryland Oncology Hematology, P.A. Columbia Maryland 21044 United States Details
Massachusetts General Hospital. Boston Massachusetts 02114 United States Details
University of Michigan Ann Arbor Michigan 48109-0934 United States Details
Mayo Clinic Rochester Rochester Minnesota 55902 United States Details
Washington University School of Medicine in St. Louis Saint Louis Missouri 63110 United States Details
Albany Medical Center Albany New York 12208 United States Details
Weill Cornell Medical College-New York Presbyterian Hospital New York New York 10021 United States Details
Oregon Health & Science University Portland Oregon 97239 United States Details
Stellar - Chance Laboratories Philadelphia Pennsylvania 19104 United States Details
Texas Oncology-Austin Midtown Austin Texas 78705 United States Details
Texas Oncology - Baylor Charles A. Sammons Cancer Center Dallas Texas 75246 United States Details
The University of Texas MD Anderson Cancer Center Houston Texas 77030-4009 United States Details
Seattle Cancer Care Alliance Seattle Washington 98109 United States Details
Beijing Cancer Hospital Beijing 100142 China Details
The affiliated Cancer Hospital, School of Medicine, UESTC Chengdu 610041 China Details
West China Hospital, Sichuan University Chengdu 610041 China Details
Chongqing Cancer Hospital Chongqing 400030 China Details
Fujian Provincial Cancer Hospital Fuzhou City 350014 China Details
First Affiliated Hospital of Gannan Medical University Ganzhou 341000 China Details
Sun Yet-sen University Cancer Center Guangzhou City 510663 China Details
Guangdong General Hospital Guangzhou 510080 China Details
Zhejiang Provincial People's Hospital Hangzhou 310014 China Details
Jinan Central Hospital Jinan City 250013 China Details
Gansu Cancer Hospital Lanzhou 730050 China Details
Fudan University Shanghai Cancer Center Shanghai City 200120 China Details
Tianjin Medical University Cancer Institute & Hospital Tianjing 300060 China Details
Tianjin Cancer Hospital Tianjin 300060 China Details
Union Hospital Tongji Medical College Huazhong University of Science and Technology Wuhan City 430023 China Details
Zhejiang Cancer Hospital Zhejiang 310022 China Details
Henan Cancer Hospital Zhengzhou 450008 China Details
Hôpital Larrey;Université Paul Sabatier Toulouse 31059 France Details
Helios Klinikum Emil von Behring GmbH Berlin 14165 Germany Details
Universitätsklinikum Essen; Innere Klinik und Poliklinik für Tumorforschung Essen 45122 Germany Details
Thoraxklinik Heidelberg gGmbH Heidelberg 69126 Germany Details
Klinikum der Universität München Muenchen 80336 Germany Details
Pius-Hospital; Klinik fuer Haematologie und Onkologie Oldenburg 26121 Germany Details
The Chinese University of Hong Kong Shatin 123456 Hong Kong Details
Ospedale Santa Maria Delle Croci Ravenna Emilia-Romagna 48100 Italy Details
Istituto Nazionale Tumori Regina Elena Roma Lazio 00144 Italy Details
IEO; Divisione di Sviluppo di Nuovi Farmaci per Terapie Innovative Milano Lombardia 20141 Italy Details
Asst Grande Ospedale Metropolitano Niguarda Milano Lombardia 20162 Italy Details
Seoul National University Hospital Seoul 03080 Korea, Republic of Details
Asan Medical Center Seoul 05505 Korea, Republic of Details
Samsung Medical Center Seoul 06351 Korea, Republic of Details
Severance Hospital, Yonsei University Health System; Oncology Seoul 120-752 Korea, Republic of Details
Antoni van Leeuwenhoek Ziekenhuis Amsterdam 1066 CX Netherlands Details
Universitair Medisch Centrum Groningen Groningen 9713 GZ Netherlands Details
National Cancer Centre Singapore 169610 Singapore Details
Institut Catala d Oncologia Hospitalet Hospitalet de Llobregat Barcelona 08908 Spain Details
Vall d´Hebron Institute of Oncology (VHIO), Barcelona Barcelona 08035 Spain Details
Hospital Clinic de Barcelona Barcelona 08036 Spain Details
Hospital Ramon y Cajal; Servicio de Oncologia Madrid 28034 Spain Details
Hospital Universitario 12 de Octubre; Servicio de Oncologia Madrid 28041 Spain Details
Taipei Veterans General Hospital Taipei City 11217 Taiwan Details
National Taiwan University Hospital Taipei 10002 Taiwan Details
Aberdeen Royal Infirmary Aberdeen AB25 2ZN United Kingdom Details
Guys and St Thomas NHS Foundation Trust, Guys Hospital London SE1 9RT United Kingdom Details
Sarah Cannon Research Institute London W1G 6AD United Kingdom Details
University College London Hospitals NHS Foundation Trust; NIHR UCLH Clinical Research Facility London W1T 7HA United Kingdom Details
The Christie NHS Foundation Trust Manchester M20 4BX United Kingdom Details
*Shaded cells indicate that there was no data available from for the field