Disease Detail

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Molecular Profile Therapy Indication/Tumor Type Response Type Profile Response Detail
KIT D816V Imatinib systemic mastocytosis resistant detail...
KIT D816V Avapritinib systemic mastocytosis sensitive detail...
KIT D816V N/A systemic mastocytosis not applicable detail...
KIT D816X N/A systemic mastocytosis not applicable detail...
CBL mutant N/A systemic mastocytosis not applicable detail...
KIT K509I Imatinib systemic mastocytosis sensitive detail...
KIT K509I Dasatinib systemic mastocytosis sensitive detail...
KIT K509I Midostaurin systemic mastocytosis predicted - sensitive detail...
KIT F522C Imatinib systemic mastocytosis sensitive detail...
Clinical Trial Phase Therapies Title Recruitment Status Covered Countries Other Countries
NCT04681105 Phase I Acetaminophen + Dexamethasone + Diphenhydramine + Flotetuzumab + Ranitidine Dexamethasone + Diphenhydramine + Flotetuzumab + Ibuprofen + Ranitidine Flotetuzumab for the Treatment of Relapsed or Refractory Advanced CD123-Positive Hematological Malignancies Recruiting USA 0
NCT04996875 Phase II PLX9486 (Apex) CGT9486 in Patients With Advanced Systemic Mastocytosis Recruiting USA | ESP 1