Disease Detail


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ID DOID:60074
Name ductal carcinoma in situ
Definition A breast carcinoma in situ that is characterized by being non-invasive, not having spread outside of the duct into the surrounding breast tissue, has_material_basis_in abnormally proliferating cells, derives_from epithelial cells.
Source DiseaseOntology.org
Alt Ids
Path disease disease of cellular proliferation pre-malignant neoplasm in situ carcinoma breast carcinoma in situ ductal carcinoma in situ


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Molecular Profile Therapy Indication/Tumor Type Response Type Profile Response Detail
Clinical Trial Phase Therapies Title Recruitment Status Covered Countries Other Countries
NCT01097278 Phase 0 Cholecalciferol S0812 High Dose Cholecalciferol in Premenopausal Women at High-Risk for Breast Cancer Completed USA 0
NCT02540330 Phase II Fulvestrant A Pre-Surgical PK Study of IM and Intraductally Delivered Fulvestrant (007) Terminated USA 0
NCT02636582 Phase II Sargramostim Nelipepimut-S Plus GM-CSF Nelipepimut-S Plus GM-CSF Vaccine Therapy in Treating Patients With Breast Cancer Completed USA 0
NCT02694809 Phase II Conjugated estrogens-bazedoxifene Conjugated Estrogens/Bazedoxifene in Treating Patients With Ductal Carcinoma in Situ Undergoing Surgery Recruiting USA 0
NCT02872025 Phase I Pembrolizumab Pembrolizumab in High-risk Ductal Carcinoma in Situ (DCIS) Recruiting USA 0
NCT02928978 Phase II Ruxolitinib Ruxolitinib for Premalignant Breast Disease Recruiting USA 0
NCT02993159 Phase II Afimoxifene Tamoxifen Testing an Active Form of Tamoxifen (4-hydroxytamoxifen) Delivered Through the Breast Skin to Control Ductal Carcinoma in Situ (DCIS) of the Breast Recruiting USA 0
NCT03535506 Phase II Palbociclib Preoperative Palbociclib in Patients With DCIS of the Breast That Are Candidates for Surgery (WI223281) Terminated USA 0
NCT04666961 Phase II Anastrozole + Tamoxifen Impact of Neoadjuvant Hormonal Therapy on the Surgical Management of Extensive Ductal Carcinomas in Situ (HORNEO01) Recruiting FRA 0