Disease Detail


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ID DOID:60076
Name estrogen-receptor negative breast cancer
Definition A breast cancer that is characterized by the absence of estrogen receptors.
Source DiseaseOntology.org
Alt Ids
Path disease disease of cellular proliferation cancer organ system cancer thoracic cancer breast cancer estrogen-receptor negative breast cancer


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Molecular Profile Therapy Indication/Tumor Type Response Type Profile Response Detail
TP53 P72R Cyclophosphamide + Doxorubicin + Fluorouracil estrogen-receptor negative breast cancer sensitive detail...
FGFR2 amp Brivanib estrogen-receptor negative breast cancer no benefit detail...
Clinical Trial Phase Therapies Title Recruitment Status Covered Countries Other Countries
NCT01471106 Phase II Dasatinib Phase II Short-term Adjuvant Therapy and Biomarker Studies With Targeted Agents in Women With Estrogen Receptor Negative Breast Cancer Active, not recruiting USA 0
NCT04020185 Phase Ib/II IMSA101 + unspecified PD-L1 antibody IMSA101 + unspecified PD-1 antibody IMSA101 Safety and Efficacy Study of IMSA101 in Refractory Malignancies Recruiting USA 0
NCT04191499 Phase II Fulvestrant + Palbociclib Fulvestrant + GDC-0077 + Palbociclib A Study Evaluating the Efficacy and Safety of Inavolisib + Palbociclib + Fulvestrant vs Placebo + Palbociclib + Fulvestrant in Patients With PIK3CA-Mutant, Hormone Receptor-Positive, Her2-Negative, Locally Advanced or Metastatic Breast Cancer Recruiting USA | ITA | FRA | ESP | DEU | CAN | BEL | AUT 17
NCT04329065 Phase II Paclitaxel + Pertuzumab + pUMVC3-IGFBP2-HER2-IGF1R vaccine + Trastuzumab Concurrent WOKVAC Vaccination, Chemotherapy, and HER2-Targeted Monoclonal Antibody Therapy Before Surgery for the Treatment of Patients With Breast Cancer Recruiting USA 0