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Drug Name huCART19
Trade Name
Synonyms huCTL019|CTL119|autologous anti-CD19 CAR-CD3zeta-4-1BB-expressing T cells
Drug Descriptions

huCART19 comprise autologous T-cells engineered to express a humanized chimeric antigen receptor (CAR) that targets CD19, as well as CD3zeta chain and 4-1BB, which may result in increased T-cell response against CD19-expressing tumor cells (NCI Drug Dictionary).

DrugClasses
CAS Registry Number NA
NCIT ID C156271

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Therapy Name Drugs Efficacy Evidence Clinical Trials
CART22-65s cells + huCART19 CART22-65s cells huCART19 0 1
huCART19 huCART19 0 3


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