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|Synonyms||huCTL019|CTL119|autologous anti-CD19 CAR-CD3zeta-4-1BB-expressing T cells|
huCART19 comprise autologous T-cells engineered to express a humanized chimeric antigen receptor (CAR) that targets CD19, as well as CD3zeta chain and 4-1BB, which may result in increased T-cell response against CD19-expressing tumor cells (NCI Drug Dictionary).
|CAS Registry Number||NA|
|Therapy Name||Drugs||Efficacy Evidence||Clinical Trials|
|CART22-65s cells + huCART19||CART22-65s cells huCART19||0||1|