Drug Detail


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Drug Name Mirzotamab clezutoclax
Trade Name
Synonyms ABBV-155|ABBV 155|ABBV155
Drug Descriptions

Mirzotamab clezutoclax (ABBV-155) is an antibody-drug conjugate (ADC) consisting of a BCL-XL inhibitor linked to a monoclonal antibody targeted against CD276 (B7H3), which may have antitumor activity (J Clin Oncol 39, no. 15_suppl (May 20, 2021) 3015).

DrugClasses BCL-XL inhibitor 14 CD276 Antibody 8
CAS Registry Number NA
NCIT ID C157279


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Therapy Name Drugs Efficacy Evidence Clinical Trials
Docetaxel + Mirzotamab clezutoclax Docetaxel Mirzotamab clezutoclax 0 1
Docetaxel + Mirzotamab clezutoclax + Paclitaxel Docetaxel Mirzotamab clezutoclax Paclitaxel 0 0
Mirzotamab clezutoclax Mirzotamab clezutoclax 0 1
Mirzotamab clezutoclax + Paclitaxel Mirzotamab clezutoclax Paclitaxel 0 1

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