Drug Detail

Contact

Missing content? – Request curation!

Request curation for specific Genes, Variants, or PubMed publications.

Have questions, comments, or suggestions? - Let us know!

Email us at : ckbsupport@jax.org

Drug Name Tipapkinogene sovacivec
Trade Name
Synonyms MVA-HPV16E6/E7-IL2|R3484|RG3484|RO5217790|TG 4001|TG-4001|TG4001
Drug Descriptions

Tipapkinogene sovacivec is a modified vaccinia virus Ankara (MVA)-based cancer vaccine, engineered to express the cytokine IL-2 and non-oncogenic versions of the human papilloma virus 16 (HPV16) proteins E6 and E7, which may lead to immune response and antitumor activity against HPV16 positive cancers (Annals of Oncology 30 Suppl 5 (2019): v494-v495; PMID: 30955915).

DrugClasses
CAS Registry Number 1052105-48-2
NCIT ID C88326

Filtering

  • Case insensitive filtering will display rows if any text in any cell matches the filter term
  • Use simple literal full or partial string matches
  • Separate multiple filter terms with a space. Any order may be used (i. e. a b c and c b a are equivalent )
  • Filtering will only apply to rows that are already loaded on the page. Filtering has no impact on query parameters.
  • Use quotes to match on a longer phrase with spaces (i.e. "mtor c1483f")

Sorting

  • Generally, the default sort order for tables is set to be first column ascending; however, specific tables may set a different default sort order.
  • Click on any column header arrows to sort by that column
  • Hold down the Shift key and click multiple columns to sort by more than one column. Be sure to set ascending or descending order for a given column before moving on to the next column.

Therapy Name Drugs Efficacy Evidence Clinical Trials
Avelumab + Tipapkinogene sovacivec Avelumab Tipapkinogene sovacivec 0 1
Tipapkinogene sovacivec Tipapkinogene sovacivec 0 0


Additional content available in CKB BOOST