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Drug Name Tipapkinogene sovacivec
Trade Name
Synonyms MVA-HPV16E6/E7-IL2|R3484|RG3484|RO5217790|TG 4001|TG-4001|TG4001
Drug Descriptions

Tipapkinogene sovacivec is a modified vaccinia virus Ankara (MVA)-based cancer vaccine, engineered to express the cytokine IL-2 and non-oncogenic versions of the human papilloma virus 16 (HPV16) proteins E6 and E7, which may lead to immune response and antitumor activity against HPV16 positive cancers (Annals of Oncology 30 Suppl 5 (2019): v494-v495; PMID: 30955915).

CAS Registry Number 1052105-48-2
NCIT ID C88326


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Therapy Name Drugs Efficacy Evidence Clinical Trials
Avelumab + Tipapkinogene sovacivec Avelumab Tipapkinogene sovacivec 0 1
Tipapkinogene sovacivec Tipapkinogene sovacivec 0 0

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