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|Synonyms||Engineered AAC Loaded with HPV16 Epitopes|
SQZ-AAC-HPV is a cell therapy comprised of autologous red blood cells engineered to express tumor-specific antigens (TAA) and human papillomavirus (HPV) type 16 epitopes and carrying a Toll-like receptor (TLR) agonist as an adjuvant, with potential to induce an anti-tumor immune response against HPV16- or TAA-expressing tumor cells (NCI Drug Dictionary).
|CAS Registry Number||NA|
|Therapy Name||Drugs||Efficacy Evidence||Clinical Trials|
|Ipilimumab + Nivolumab + SQZ-AAC-HPV||Ipilimumab Nivolumab SQZ-AAC-HPV||0||1|
|Ipilimumab + SQZ-AAC-HPV||Ipilimumab SQZ-AAC-HPV||0||1|