Drug Detail


Missing content? – Request curation!

Request curation for specific Genes, Variants, or PubMed publications.

Have questions, comments, or suggestions? - Let us know!

Email us at : ckbsupport@jax.org

Drug Name SHR-1316
Trade Name
Synonyms SHR 1316|SHR1316|Adebrelimab|HTI 1088|HTI-1088|HTI1088
Drug Descriptions

SHR-1316 is a monoclonal antibody that targets PD-L1 (CD274), potentially resulting in antitumor activity (PMID: 33760397).

DrugClasses Immune Checkpoint Inhibitor 148 PD-L1/PD-1 antibody 117
CAS Registry Number NA
NCIT ID C148535


  • Case insensitive filtering will display rows if any text in any cell matches the filter term
  • Use simple literal full or partial string matches
  • Separate multiple filter terms with a space. Any order may be used (i. e. a b c and c b a are equivalent )
  • Filtering will only apply to rows that are already loaded on the page. Filtering has no impact on query parameters.
  • Use quotes to match on a longer phrase with spaces (i.e. "mtor c1483f")


  • Generally, the default sort order for tables is set to be first column ascending; however, specific tables may set a different default sort order.
  • Click on any column header arrows to sort by that column
  • Hold down the Shift key and click multiple columns to sort by more than one column. Be sure to set ascending or descending order for a given column before moving on to the next column.

Therapy Name Drugs Efficacy Evidence Clinical Trials
Carboplatin + Nab-paclitaxel + SHR-1316 Carboplatin Nab-paclitaxel SHR-1316 0 0
Fluorouracil + Liposomal irinotecan + SHR-1316 Fluorouracil Liposomal irinotecan SHR-1316 0 0
Fluzoparib + SHR-1316 Fluzoparib SHR-1316 0 0
IBI310 + SHR-1316 IBI310 SHR-1316 0 0
SHR-1316 SHR-1316 0 0
SHR-1316 + SHR-2002 SHR-1316 SHR-2002 0 1
SHR-1316 + SHR1501 SHR-1316 SHR1501 0 1

Additional content available in CKB BOOST