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Drug Name | JSKN003 |
Trade Name | |
Synonyms | JSKN 003|JSKN-003 |
Drug Descriptions |
JSKN003 is an antibody-drug conjugate (ADC) comprising a bispecific antibody targeting two epitopes of ERBB2 (HER2) linked to a topoisomerase inhibitor, which potentially induces cell cycle arrest and apoptosis of ERBB2 (HER2)-expressing tumor cells and results in antitumor activity (J Clin Oncol 42, 2024 (suppl 16; abstr 3038), NCI Drug Dictionary). |
DrugClasses | HER2 (ERBB2) Antibody 75 HER2 (ERBB2) Antibody-Drug Conjugate 29 |
CAS Registry Number | NA |
NCIT ID | C190145 |
Therapy Name | Drugs | Efficacy Evidence | Clinical Trials |
---|---|---|---|
JSKN003 | JSKN003 | 0 | 1 |