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Drug Name | CD38-SADA |
Trade Name | |
Synonyms | Anti-CD38 scFv/Anti-DOTA scFv Fusion Protein CD38-SADA |
Drug Descriptions |
CD38-SADA is a fusion protein comprising a single chain variable fragment targeting CD38, a single chain variable fragment targeting the chelating agent DOTA, and a self-assembling and disassembling (SADA) domain, which potentially allows selective delivery of a radioactive payload to CD38-expressing tumor cells (NCI Drug Dictionary). |
DrugClasses | CD38 Antibody 20 |
CAS Registry Number | NA |
NCIT ID | C201289 |
Therapy Name | Drugs | Efficacy Evidence | Clinical Trials |
---|---|---|---|
CD38-SADA | CD38-SADA | 0 | 0 |
CD38-SADA + Lutetium Lu 177-DOTA | CD38-SADA Lutetium Lu 177-DOTA | 0 | 1 |