Drug Detail


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Drug Name Fingolimod
Trade Name Gilenya
Synonyms FTY720
Drug Descriptions

Gilenya (fingolimod) is a sphingosine 1-phosphate receptor modulator that activates PP2A, which may result in restoration of tumor suppressor activity thereby leading to apoptosis and inhibition of cell proliferation (PMID: 24448818). Gilenya (fingolimod) is FDA approved for multiple sclerosis (FDA.gov).

DrugClasses PP2A Activator 7
CAS Registry Number 162359-55-9
NCIT ID C74202


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Therapy Name Drugs Efficacy Evidence Clinical Trials
Daunorubicin + Fingolimod Daunorubicin Fingolimod 1 0
Fingolimod Fingolimod 2 1
Fingolimod + Gemcitabine Fingolimod Gemcitabine 0 0
Fingolimod + Sorafenib Fingolimod Sorafenib 0 0

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