Drug Detail


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Drug Name AZD1480
Trade Name
Synonyms AZD-1480
Drug Descriptions

AZD1480 is an ATP-competitive inhibitor of JAK1 and JAK2, which reduces STAT3 activation, potentially resulting in decreased tumor growth (PMID: 22027691, PMID: 24158701) and has been also shown to inhibit ALK, LTK, FGFR1-3, RET and TRKA-C kinases (PMID: 29312610).

DrugClasses JAK1 Inhibitor - ATP competitive 5 JAK2 Inhibitor - ATP competitive 15
CAS Registry Number 935666-88-9
NCIT ID C91394


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Therapy Name Drugs Efficacy Evidence Clinical Trials
AZD1480 AZD1480 12 0
AZD1480 + CUDC-907 AZD1480 CUDC-907 1 0

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