Drug Detail

Drug Name Glesatinib
Trade Name
Synonyms MGCD265
Drug Descriptions

Glesatinib (MGCD265) inhibits several tyrosine kinases including MET, MST1R (RON), and AXL, as well as VEGFR1-3, and TIE2, which may result in decreased tumor growth (PMID: 25806189, PMID: 26555154).

DrugClasses AXL Inhibitor 24 MET Inhibitor 51 RON Inhibitor 10 VEGFR Inhibitor (Pan) 31

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Therapy Name Drugs Efficacy Evidence Clinical Trials
Docetaxel + Glesatinib Docetaxel Glesatinib 1 1
Erlotinib + Glesatinib Erlotinib Glesatinib 3 1
Glesatinib Glesatinib 23 2
Glesatinib + Nivolumab Glesatinib Nivolumab 0 1


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