Drug Detail


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Drug Name Brivanib
Trade Name
Synonyms BMS-540215|BMS540215
Drug Descriptions

Brivanib (BMS-540215) selectively binds and inhibits KDR (VEGFR2), while demonstrating moderate activity against VEGFR1 and FGFR1, which inhibits tumor angiogenesis, tumor cell growth, and induces tumor regression (PMID: 18829493, PMID: 16570908, PMID: 32434345, PMID: 31522033).

DrugClasses FGFR1 Inhibitor 28 VEGFR1 Inhibitor 6 VEGFR2 Inhibitor 37
CAS Registry Number 649735-46-6
NCIT ID C67040


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Therapy Name Drugs Efficacy Evidence Clinical Trials
Brivanib Brivanib 12 0

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