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Drug Name Rigosertib Sodium
Trade Name
Synonyms ON 01910.Na|SyB L-1101
Drug Descriptions

Rigosertib (ON 01910.Na) inhibits polo-like kinase 1 (Plk1) and PI3K pathways, which induces selective G2/M arrest and apoptosis in tumor cells (PMID: 24777753).

DrugClasses PI3K Inhibitor (Pan) 40 PLK1 Inhibitor 18
CAS Registry Number 592542-60-4
NCIT ID C71355

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Therapy Name Drugs Efficacy Evidence Clinical Trials
Gemcitabine + Rigosertib Sodium Gemcitabine Rigosertib Sodium 0 0
Palbociclib + Rigosertib Sodium Palbociclib Rigosertib Sodium 0 0
Rigosertib Sodium Rigosertib Sodium 6 4


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