Drug Detail


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Drug Name HMN-214
Trade Name
Drug Descriptions

HMN-214 is a prodrug of the active agent HMN-176, which interferes with the location of PLK1, leading to cell cycle arrest, destruction of the spindle polar bodies, and DNA fragmentation (PMID: 19474163, PMID: 16951237).

DrugClasses PLK1 Inhibitor 18
CAS Registry Number 173529-46-9


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Therapy Name Drugs Efficacy Evidence Clinical Trials
HMN-214 HMN-214 0 0
HMN-214 + Palbociclib HMN-214 Palbociclib 1 0

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