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Drug Name Bardoxolone methyl
Trade Name
Synonyms CDDO-Me|RTA 402
Drug Descriptions

Bardoxolone methyl (CDDO-Me) is a derivative of a synthetic triterpenoid, 2-cyano-3,12-dioxooleana- 1,9-dien-28-oic acid (CDDO), which targets KEAP1, leading to the activation of NRF2, and also binds to IKKB and inhibits NF-KB activation. CDDO-Me is developed for the treatment of inflammation and cancer (PMID: 25364233, PMID: 32370011)

DrugClasses
CAS Registry Number 218600-53-4
NCIT ID C98250

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Therapy Name Drugs Efficacy Evidence Clinical Trials
Bardoxolone methyl Bardoxolone methyl 0 0


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