Drug Detail


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Drug Name Vofatamab
Trade Name
Synonyms B-701|MFGR1877S|RG-7444|R3Mab
Drug Descriptions

Vofatamab (B-701) is a monoclonal antibody, which binds FGFR3 to prevent phosphorylation and signaling, thereby inhibiting proliferation and promoting apoptosis in cancer cells (Journal of Clinical Oncology 36, no. 15_suppl (May 20 2018) 4534-4534, PMID: 22203368).

DrugClasses FGFR3 Antibody 3
CAS Registry Number 1312305-12-6
NCIT ID C116863


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Therapy Name Drugs Efficacy Evidence Clinical Trials
225Ac-FPI-1966 + Vofatamab 225Ac-FPI-1966 Vofatamab 0 1
Atezolizumab + Vofatamab Atezolizumab Vofatamab 0 1
Docetaxel + Vofatamab Docetaxel Vofatamab 2 1
Pembrolizumab + Vofatamab Pembrolizumab Vofatamab 0 1
Vofatamab Vofatamab 8 1

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