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BMS-986156 is an activating monoclonal antibody that binds to TNFRSF18 (GITR, CD357), which leads to the activation of effector T cells and a decrease in T-regulatory cells, subsequently resulting in antitumor activity (Journal of Clinical Oncology 35, no. 15_suppl (May 2017) 104-104, PMID: 31697308).
|DrugClasses||GITR Antibody 6|
|CAS Registry Number||NA|
|Therapy Name||Drugs||Efficacy Evidence||Clinical Trials|
|BMS-986156 + Ipilimumab + Nivolumab||BMS-986156 Ipilimumab Nivolumab||0||1|
|BMS-986156 + Nivolumab||BMS-986156 Nivolumab||0||2|