Drug Detail


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Drug Name TRX518
Trade Name
Synonyms TRX-518|TRX 518
Drug Descriptions

TRX518 is an activating monoclonal antibody to the glucocorticoid-induced tumor necrosis factor receptor, TNFRSF18 (GITR, CD357), that blocks GITR signaling, leading to activation of immune response (PMID: 31036879).

DrugClasses GITR Antibody 6
CAS Registry Number NA
NCIT ID C95023


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Therapy Name Drugs Efficacy Evidence Clinical Trials
Avelumab + Cyclophosphamide + TRX518 Avelumab Cyclophosphamide TRX518 0 1
TRX518 TRX518 0 2

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