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TRX518 is an activating monoclonal antibody to the glucocorticoid-induced tumor necrosis factor receptor, TNFRSF18 (GITR, CD357), that blocks GITR signaling, leading to activation of immune response (NCI Drug Dictionary).
|DrugClasses||GITR Antibody 6|
|Therapy Name||Drugs||Efficacy Evidence||Clinical Trials|
|Avelumab + Cyclophosphamide + TRX518||Avelumab Cyclophosphamide TRX518||0||1|