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Drug Name Custirsen
Trade Name
Synonyms Antisense Clusterin|Antisense TRPM-2|OGX-011|CC-8490
Drug Descriptions

Custirsen (OGX-011) is an antisense oligo targeting clusterin, which leads to apoptosis in tumor cells (PMID: 23130925, PMID: 30732140).

CAS Registry Number 890056-27-6
NCIT ID C169869


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Therapy Name Drugs Efficacy Evidence Clinical Trials
Carboplatin + Custirsen + Gemcitabine Carboplatin Custirsen Gemcitabine 0 0
Cisplatin + Custirsen + Gemcitabine Cisplatin Custirsen Gemcitabine 0 0
Custirsen Custirsen 0 0
Custirsen + Docetaxel Custirsen Docetaxel 0 1
Custirsen + Docetaxel + Prednisone Custirsen Docetaxel Prednisone 0 0
Custirsen + Mitoxantrone + Prednisone Custirsen Mitoxantrone Prednisone 0 0

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