Drug Detail


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Drug Name AT13148
Trade Name
Synonyms AT-13148|AT 13148
Drug Descriptions

AT13148 is a small molecule ATP-competitive inhibitor of AGC kinases including AKT1, AKT2, AKT3, p70S6K (RPS6KB1), PKA (PRKACA), ROCK1, ROCK2, RSK1, and SGK3, which results in decreased growth of tumor cells (PMID: 22781553, PMID: 25840982, PMID: 32616501).

DrugClasses AKT Inhibitor (Pan) - ATP competitive 7 PKA Inhibitor 2
CAS Registry Number 1056901-62-2
NCIT ID C101786


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Therapy Name Drugs Efficacy Evidence Clinical Trials
AT13148 AT13148 3 0

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