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Drug Name Taletrectinib
Trade Name
Synonyms DS6051b|DS-6051B|DS-6051|AB-106
Drug Descriptions

Taletrectinib (DS6051b) is an inhibitor of NTRK1/2/3 and ROS1 fusion proteins, which blocks downstream signaling and may lead to inhibition of tumor cell growth (PMID: 32591465).

DrugClasses ROS1 Inhibitor 19 Trk Receptor Inhibitor (Pan) 29
CAS Registry Number 1505515-69-4
NCIT ID C118948

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Therapy Name Drugs Efficacy Evidence Clinical Trials
SHP099 + Taletrectinib SHP099 Taletrectinib 0 0
Taletrectinib Taletrectinib 5 2


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