Drug Detail


Missing content? – Request curation!

Request curation for specific Genes, Variants, or PubMed publications.

Have questions, comments, or suggestions? - Let us know!

Email us at : ckbsupport@jax.org

Drug Name AdV-tk
Trade Name
Synonyms Aglatimagene besadenovec|GliAtak|ProstAtak|CAN-2409|CAN2409|Virafir
Drug Descriptions

ADV-tk (aglatimagene besadenovec) is an engineered adenoviral vector expressing the herpes simplex virus thymidine kinase that sensitizes tumor cells to therapy with acyclic guanosine analogues (PMID: 26843484, PMID: 30883662).

CAS Registry Number 1621271-62-2
NCIT ID C73996


  • Case insensitive filtering will display rows if any text in any cell matches the filter term
  • Use simple literal full or partial string matches
  • Separate multiple filter terms with a space. Any order may be used (i. e. a b c and c b a are equivalent )
  • Filtering will only apply to rows that are already loaded on the page. Filtering has no impact on query parameters.
  • Use quotes to match on a longer phrase with spaces (i.e. "mtor c1483f")


  • Generally, the default sort order for tables is set to be first column ascending; however, specific tables may set a different default sort order.
  • Click on any column header arrows to sort by that column
  • Hold down the Shift key and click multiple columns to sort by more than one column. Be sure to set ascending or descending order for a given column before moving on to the next column.

Therapy Name Drugs Efficacy Evidence Clinical Trials
Acyclovir + AdV-tk Acyclovir AdV-tk 0 1
AdV-tk AdV-tk 0 2
AdV-tk + Nivolumab AdV-tk Nivolumab 0 1
AdV-tk + Valacyclovir AdV-tk Valacyclovir 0 6

Additional content available in CKB BOOST