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Drug Name | Zibotentan |
Trade Name | |
Synonyms | ZD4054 |
Drug Descriptions |
Zibotentan (ZD4054) is an antagonist of the ET(A) endothelin receptor, which results in decreased ET-1/ET(A)-mediated signaling, and may lead to decreased proliferation and increased apoptosis of tumor cells and reduced tumor growth (PMID: 17620430, PMID: 18616419, PMID: 30937921). |
DrugClasses | |
CAS Registry Number | 186497-07-4 |
NCIT ID | C48430 |
Therapy Name | Drugs | Efficacy Evidence | Clinical Trials |
---|---|---|---|
Zibotentan | Zibotentan | 0 | 0 |