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Drug Name Debio 0617B
Trade Name
Drug Descriptions

Debio 0617B is a multi-kinase inhibitor of SRC, JAK, and ABL, the class III kinases, CSF1R, FLT3, KIT, and PDGFR, and the class V kinases, VEGFR 1/2/3, which may result in inhibition of Stat3 and Stat5 signaling, leading to inhibition of tumor cell growth and metastasis (PMID: 27439479, PMID: 28468777).

DrugClasses ABL Inhibitor (pan) 9 CSF1R Inhibitor 26 FLT3 Inhibitor 57 JAK Inhibitor (Pan) 8 KIT Inhibitor 52 PDGFR Inhibitor (Pan) 27 SRC Inhibitor 31 VEGFR Inhibitor (Pan) 33
CAS Registry Number 1332329-27-7


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Therapy Name Drugs Efficacy Evidence Clinical Trials
Debio 0617B Debio 0617B 0 0
Debio 0617B + Erlotinib Debio 0617B Erlotinib 0 0

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