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Drug Name | CS-11 |
Trade Name | |
Synonyms | |
Drug Descriptions |
CS-11 binds to PR55-alpha, the regulatory subunit of PP2A, resulting in decreased nuclear beta-catenin activity and reduced expression of downstream targets and increased cell surface levels of E-cadherin and activated beta-catenin, which may lead to increased tumor cell apoptosis and decreased metastasis (PMID: 28500231). |
DrugClasses | |
CAS Registry Number | NA |
NCIT ID | NA |
Therapy Name | Drugs | Efficacy Evidence | Clinical Trials |
---|---|---|---|
CS-11 | CS-11 | 0 | 0 |