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Therapy Name | CS-11 |
Synonyms | |
Therapy Description |
CS-11 binds to PR55-alpha, the regulatory subunit of PP2A, resulting in decreased nuclear beta-catenin activity and reduced expression of downstream targets and increased cell surface levels of E-cadherin and activated beta-catenin, which may lead to increased tumor cell apoptosis and decreased metastasis (PMID: 28500231). |
Drug Name | Trade Name | Synonyms | Drug Classes | Drug Description |
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CS-11 | CS-11 binds to PR55-alpha, the regulatory subunit of PP2A, resulting in decreased nuclear beta-catenin activity and reduced expression of downstream targets and increased cell surface levels of E-cadherin and activated beta-catenin, which may lead to increased tumor cell apoptosis and decreased metastasis (PMID: 28500231). |
Molecular Profile | Indication/Tumor Type | Response Type | Therapy Name | Approval Status | Evidence Type | Efficacy Evidence | References |
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Clinical Trial | Phase | Therapies | Title | Recruitment Status | Covered Countries | Other Countries |
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