Drug Detail


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Drug Name TAK-243
Trade Name
Synonyms MLN7243
Drug Descriptions

TAK-243 (MLN7243) is an inhibitor that selectively targets the ubiquitin activating enzyme, UBA1, which may result in inhibition of ubiquitination related processes such as cell cycle progression, apoptotic regulation, and DNA damage response (Mol Cancer Ther 2015;14(12 Suppl 2):Abstract nr A164, PMID: 28711351).

CAS Registry Number 1450833-55-2
NCIT ID C113788


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Therapy Name Drugs Efficacy Evidence Clinical Trials
Carboplatin + TAK-243 Carboplatin TAK-243 0 0
Docetaxel + TAK-243 Docetaxel TAK-243 0 0
Radiotherapy + TAK-243 Radiotherapy TAK-243 0 0
TAK-243 TAK-243 0 0

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