Drug Detail

Contact

Missing content? – Request curation!

Request curation for specific Genes, Variants, or PubMed publications.

Have questions, comments, or suggestions? - Let us know!

Email us at : ckbsupport@jax.org

Drug Name LY3381916
Trade Name
Synonyms LY-3381916|LY 3381916
Drug Descriptions

LY3381916 binds to and inhibits indoleamine 2,3-dioxygenase 1 (IDO1), resulting in decreased conversion of tryptophan to kynurenine and potentially leading to increased activation of immune response against tumor cells (NCI Thesaurus).

DrugClasses IDO1 Inhibitor 12
CAS Registry Number NA
NCIT ID C143068

Filtering

  • Case insensitive filtering will display rows if any text in any cell matches the filter term
  • Use simple literal full or partial string matches
  • Separate multiple filter terms with a space. Any order may be used (i. e. a b c and c b a are equivalent )
  • Filtering will only apply to rows that are already loaded on the page. Filtering has no impact on query parameters.
  • Use quotes to match on a longer phrase with spaces (i.e. "mtor c1483f")

Sorting

  • Generally, the default sort order for tables is set to be first column ascending; however, specific tables may set a different default sort order.
  • Click on any column header arrows to sort by that column
  • Hold down the Shift key and click multiple columns to sort by more than one column. Be sure to set ascending or descending order for a given column before moving on to the next column.

Therapy Name Drugs Efficacy Evidence Clinical Trials
LY3300054 + LY3381916 LY3300054 LY3381916 0 1
LY3381916 LY3381916 0 1


Additional content available in CKB BOOST