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Drug Name | ONO-7475 |
Trade Name | |
Synonyms | ONO7475 |
Drug Descriptions |
ONO-7475 inhibits AXL, MERTK, FLT3, and TYRO3, potentially leading to reduced growth and increased apoptosis of tumor cells (PMID: 28912176, PMID: 30501104, PMID: 31953310). |
DrugClasses | AXL Inhibitor 29 FLT3 Inhibitor 64 MERTK Inhibitor 13 TYRO3 Inhibitor 8 |
CAS Registry Number | 1646839-59-9 |
NCIT ID | C136822 |
Therapy Name | Drugs | Efficacy Evidence | Clinical Trials |
---|---|---|---|
Cytarabine + ONO-7475 | Cytarabine ONO-7475 | 1 | 0 |
ONO-7475 | ONO-7475 | 2 | 1 |
ONO-7475 + Venetoclax | ONO-7475 Venetoclax | 1 | 0 |