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Drug Name ONO-7475
Trade Name
Synonyms ONO7475
Drug Descriptions

ONO-7475 inhibits AXL, MERTK, FLT3, and TYRO3, potentially leading to reduced growth and increased apoptosis of tumor cells (PMID: 28912176, PMID: 30501104, PMID: 31953310).

DrugClasses AXL Inhibitor 28 FLT3 Inhibitor 61 MERTK Inhibitor 13 TYRO3 Inhibitor 8
CAS Registry Number 1646839-59-9
NCIT ID C136822

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Therapy Name Drugs Efficacy Evidence Clinical Trials
Cytarabine + ONO-7475 Cytarabine ONO-7475 1 0
ONO-7475 ONO-7475 2 1
ONO-7475 + Venetoclax ONO-7475 Venetoclax 1 0


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