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Drug Name Eftilagimod alpha
Trade Name
Synonyms IMP321|LAG-31g|Immufact
Drug Descriptions

Eftilagimod alpha (IMP321) is a recombinant soluble LAG3 protein, which binds to MHC Class II molecules, resulting in increased dendritic cell maturation and potentially leading to enhanced anti-tumor immune response (PMID: 16621192, PMID: 17785860, PMID: 20653948, PMID: 30977393).

CAS Registry Number 1800476-36-1
NCIT ID C62509


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Therapy Name Drugs Efficacy Evidence Clinical Trials
Avelumab + Eftilagimod alpha Avelumab Eftilagimod alpha 0 1
Eftilagimod alpha Eftilagimod alpha 0 1
Eftilagimod alpha + Paclitaxel Eftilagimod alpha Paclitaxel 0 1
Eftilagimod alpha + Pembrolizumab Eftilagimod alpha Pembrolizumab 0 2

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