Drug Detail


Missing content? – Request curation!

Request curation for specific Genes, Variants, or PubMed publications.

Have questions, comments, or suggestions? - Let us know!

Email us at : ckbsupport@jax.org

Drug Name LAE001
Trade Name
Synonyms LAE-001|LAE 001|CFG920|CFG-920|CFG 920
Drug Descriptions

LAE001 (CFG920) inhibits CYP17, resulting in decreased androgen production and potentially leading to reduced proliferation of androgen-dependent tumor cells (PMID: 23880851, PMID: 26954621).

DrugClasses Hormone - Anti-androgens 48
CAS Registry Number 1260006-20-9
NCIT ID C102855


  • Case insensitive filtering will display rows if any text in any cell matches the filter term
  • Use simple literal full or partial string matches
  • Separate multiple filter terms with a space. Any order may be used (i. e. a b c and c b a are equivalent )
  • Filtering will only apply to rows that are already loaded on the page. Filtering has no impact on query parameters.
  • Use quotes to match on a longer phrase with spaces (i.e. "mtor c1483f")


  • Generally, the default sort order for tables is set to be first column ascending; however, specific tables may set a different default sort order.
  • Click on any column header arrows to sort by that column
  • Hold down the Shift key and click multiple columns to sort by more than one column. Be sure to set ascending or descending order for a given column before moving on to the next column.

Therapy Name Drugs Efficacy Evidence Clinical Trials
Afuresertib + LAE001 + Prednisone Afuresertib LAE001 Prednisone 0 1
LAE001 LAE001 0 0

Additional content available in CKB BOOST