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Y27632 is an inhibitor of Rho-associated protein kinase (ROCK1), which may block cellular adhesion, and lead to inhibition of colony formation and enhancement of cell detachment when combined with chemotherapeutic agents (PMID: 31160603, PMID: 23392171).
|CAS Registry Number||146986-50-7|
|Therapy Name||Drugs||Efficacy Evidence||Clinical Trials|
|Paclitaxel + Y27632||Paclitaxel Y27632||0||0|