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Drug Name PRT543
Trade Name
Synonyms PRT-543|PRT 543
Drug Descriptions

PRT543 is an inhibitor of PRMT5, which inhibits PRMT5 methyltransferase activity, leading to decreased histone H2A, H3, and H4 arginine mono and di-methylation and altered expression of genes involved in cellular processes, thereby potentially resulting in decreased tumor cell growth (NCI Drug Dictionary).

DrugClasses PRMT5 Inhibitor 16
CAS Registry Number NA
NCIT ID C162454

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Therapy Name Drugs Efficacy Evidence Clinical Trials
PRT543 PRT543 0 1


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