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Drug Name | Anti-hCD70 CAR T cells |
Trade Name | |
Synonyms | |
Drug Descriptions |
Anti-hCD70 CAR T cells consist of patient-derived peripheral blood lymphocytes that have been transduced with a retroviral vector expressing a chimeric antigen receptor (CAR) that targets CD70 and contains the extracellular region of CD27 fused to 41BB and CD3-zeta, which potentially inhibit the growth of CD70-expressing tumors (PMID: 27803044). |
DrugClasses | |
CAS Registry Number | NA |
NCIT ID | C129593 |
Therapy Name | Drugs | Efficacy Evidence | Clinical Trials |
---|---|---|---|
Aldesleukin + Anti-hCD70 CAR T cells | Aldesleukin Anti-hCD70 CAR T cells | 0 | 1 |
Anti-hCD70 CAR T cells | Anti-hCD70 CAR T cells | 0 | 0 |